Molecular Sieve Supported Lanthanum Catalyst for the Efficient Synthesis of Polyhydroquinolines via Hantzsch Synthesis

Authors

  • Ágnes Magyar
    Affiliation

    Budapest University of Technology and Economics

  • Zoltán Hell
    Affiliation

    Budapest University of Technology and Economics

https://doi.org/10.3311/PPch.10655

Abstract

Molecular sieve supported lanthanum catalyst proved to be an efficient heterogeneous catalyst for the one-pot, four-component synthesis of polyhydroquinoline derivatives from aromatic aldehydes, dimedone, ethyl acetoacetate and ammonium acetate in ethanol via Hantzsch reaction. The method has several advantages such as simple reaction conditions, short reaction time, high yields and simple workup procedure, which make it an attractive route for the synthesis of polyhydroquinolines. The catalyst could be reused several times without the loss of its initial activity.

Keywords:

Lanthanum, polyhydroquinolines, Hantzsch reaction, multicomponent reaction, 4 Å molecular sieve, heterogeneous catalysis

Published Online

2017-07-03

How to Cite

Magyar, Ágnes, Hell, Z. “Molecular Sieve Supported Lanthanum Catalyst for the Efficient Synthesis of Polyhydroquinolines via Hantzsch Synthesis”, Periodica Polytechnica Chemical Engineering, 61(4), pp. 278–282, 2017. https://doi.org/10.3311/PPch.10655

Issue

Section

Articles