Molecular Sieve Supported Lanthanum Catalyst for the Efficient Synthesis of Polyhydroquinolines via Hantzsch Synthesis

  • Ágnes Magyar Budapest University of Technology and Economics
  • Zoltán Hell Budapest University of Technology and Economics

Abstract

Molecular sieve supported lanthanum catalyst proved to be an efficient heterogeneous catalyst for the one-pot, four-component synthesis of polyhydroquinoline derivatives from aromatic aldehydes, dimedone, ethyl acetoacetate and ammonium acetate in ethanol via Hantzsch reaction. The method has several advantages such as simple reaction conditions, short reaction time, high yields and simple workup procedure, which make it an attractive route for the synthesis of polyhydroquinolines. The catalyst could be reused several times without the loss of its initial activity.

Keywords

Lanthanum, polyhydroquinolines, Hantzsch reaction, multicomponent reaction, 4 Å molecular sieve, heterogeneous catalysis
Published
03-07-2017
How to Cite
MAGYAR, Ágnes; HELL, Zoltán. Molecular Sieve Supported Lanthanum Catalyst for the Efficient Synthesis of Polyhydroquinolines via Hantzsch Synthesis. Periodica Polytechnica Chemical Engineering, [S.l.], july 2017. ISSN 1587-3765. Available at: <https://pp.bme.hu/ch/article/view/10655>. Date accessed: 24 sep. 2017. doi: https://doi.org/10.3311/PPch.10655.
Section
Articles