Pharmaceutical and Macromolecular Technologies in the Spirit of Industry 4.0

  • György Marosi FirePharma group, FIEK-PharmaTech Laboratory, FlowBiotech Center, Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, H-1111 Budapest, Műegyetem rkp. 3., Hungary
  • Edit Hirsch FirePharma group, FIEK-PharmaTech Laboratory, FlowBiotech Center, Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, H-1111 Budapest, Műegyetem rkp. 3., Hungary
  • Katalin Bocz FirePharma group, FIEK-PharmaTech Laboratory, FlowBiotech Center, Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, H-1111 Budapest, Műegyetem rkp. 3., Hungary
  • Andrea Toldy Department of Polymer Engineering, Faculty of Mechanical Engineering, Budapest University of Technology and Economics, H-1111 Budapest, Műegyetem rkp. 3., Hungary
  • Beáta Szolnoki FirePharma group, FIEK-PharmaTech Laboratory, FlowBiotech Center, Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, H-1111 Budapest, Műegyetem rkp. 3., Hungary
  • Brigitta Bodzay FirePharma group, FIEK-PharmaTech Laboratory, FlowBiotech Center, Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, H-1111 Budapest, Műegyetem rkp. 3., Hungary
  • István Csontos FirePharma group, FIEK-PharmaTech Laboratory, FlowBiotech Center, Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, H-1111 Budapest, Műegyetem rkp. 3., Hungary
  • Attila Farkas FirePharma group, FIEK-PharmaTech Laboratory, FlowBiotech Center, Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, H-1111 Budapest, Műegyetem rkp. 3., Hungary
  • Attila Balogh FirePharma group, FIEK-PharmaTech Laboratory, FlowBiotech Center, Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, H-1111 Budapest, Műegyetem rkp. 3., Hungary
  • Balázs Démuth FirePharma group, FIEK-PharmaTech Laboratory, FlowBiotech Center, Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, H-1111 Budapest, Műegyetem rkp. 3., Hungary
  • Zsombor K. Nagy FirePharma group, FIEK-PharmaTech Laboratory, FlowBiotech Center, Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, H-1111 Budapest, Műegyetem rkp. 3., Hungary
  • Hajnalka Pataki FirePharma group, FIEK-PharmaTech Laboratory, FlowBiotech Center, Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, H-1111 Budapest, Műegyetem rkp. 3., Hungary

Abstract

Well designed (multilayer, adaptive, reactive) interphases, being a key element of multicomponent structures, could be tailored to different requirements through controlled technologies. This is the link connecting various green, safe, healthy materials and innovative pharmaceuticals. Upgraded recycling could be performed by interfacial consolidation of self-reinforced composites, the flame retardancy of which is feasible with surprisingly low amount of flame retardant. Examples are shown how the reinforced and foamed forms of thermosetting and thermoplastic biopolymers can play a significant role (after flame retardant modification) in the development of airplanes and electric cars. Biopolymer nanofibres, such as polycaprolactone and polyhydroxybutyrate, could be formed with increased productivity for various medical uses. Raman-based control of the units of integrated continuous technologies has been elaborated including controlled formation of crystals with polymer interlayer for direct tableting.

Keywords: interface modification, recycling, biocomposites, pharmaceutical crystallization, Raman control
Published online
2018-11-09
How to Cite
Marosi, G., Hirsch, E., Bocz, K., Toldy, A., Szolnoki, B., Bodzay, B., Csontos, I., Farkas, A., Balogh, A., Démuth, B., Nagy, Z. and Pataki, H. (2018) “Pharmaceutical and Macromolecular Technologies in the Spirit of Industry 4.0”, Periodica Polytechnica Chemical Engineering, 62(4), pp. 457–466. doi: https://doi.org/10.3311/PPch.12870.
Section
Articles