Pressurized Liquid Extraction of Hemp Residue and Purification of the Extract with Liquid-Liquid Extraction

Authors

  • János Béri ORCID
    Affiliation

    Department of Chemical and Environmental Process Engineering, Faculty of Chemical Technology and Biotechnology, Budapest University of Technology and Economics, H-1111 Budapest, Műegyetem rkp. 3., Hungary

  • Sára Nagy
    Affiliation

    Department of Chemical and Environmental Process Engineering, Faculty of Chemical Technology and Biotechnology, Budapest University of Technology and Economics, H-1111 Budapest, Műegyetem rkp. 3., Hungary

  • Ádám Kolay Kovács ORCID
    Affiliation

    Department of Chemical and Environmental Process Engineering, Faculty of Chemical Technology and Biotechnology, Budapest University of Technology and Economics, H-1111 Budapest, Műegyetem rkp. 3., Hungary

  • Erika Vági ORCID
    Affiliation

    Department of Chemical and Environmental Process Engineering, Faculty of Chemical Technology and Biotechnology, Budapest University of Technology and Economics, H-1111 Budapest, Műegyetem rkp. 3., Hungary

  • Edit Székely ORCID
    Affiliation

    Department of Chemical and Environmental Process Engineering, Faculty of Chemical Technology and Biotechnology, Budapest University of Technology and Economics, H-1111 Budapest, Műegyetem rkp. 3., Hungary

https://doi.org/10.3311/PPch.18456

Abstract

The first semi-continuous Pressurized Liquid Extraction (PLE) of hemp threshing residue with ethanol was carried out according to a 32 full factorial experimental design with pressure and temperature as independent variables at 8-10-12 MPa and 323-333-343 K, respectively. The total- and cannabidiol (CBD) yield curves were fitted to the modified two-parameter Brunner equation. Best results, concerning CBD, can be achieved at 12 MPa and 343 K. Solvent mass-consumption and operation time were considerably decreased compared to a previous supercritical fluid extraction study on the same material. Furthermore, the concentration profiles were evaluated to study the mass transfer. The winterized dry extracts were further studied in a methanol-hexane-water ternary system concerning CBD distribution ratio, showing high methanol dependency.

Keywords:

hemp threshing residue, solid-liquid extraction, PLE, CBD, distribution coefficient, ternary mixture

Published Online

2021-11-26

How to Cite

Béri, J., Nagy, S., Kolay Kovács, Ádám, Vági, E., Székely, E. “Pressurized Liquid Extraction of Hemp Residue and Purification of the Extract with Liquid-Liquid Extraction”, Periodica Polytechnica Chemical Engineering, 66(1), pp. 82–90, 2022. https://doi.org/10.3311/PPch.18456

Issue

Section

Articles