Recent List of Cyclodextrin-Containing Drug Products

Authors

  • István Puskás ORCID
    Affiliation

    CycloLab Cyclodextrin Research Ltd., 7 Illatos str., H-1097 Budapest, Hungary

  • Lajos Szente ORCID
    Affiliation

    CycloLab Cyclodextrin Research Ltd., 7 Illatos str., H-1097 Budapest, Hungary

  • Levente Szőcs
    Affiliation

    CycloLab Cyclodextrin Research Ltd., 7 Illatos str., H-1097 Budapest, Hungary

  • Éva Fenyvesi ORCID
    Affiliation

    CycloLab Cyclodextrin Research Ltd., 7 Illatos str., H-1097 Budapest, Hungary

https://doi.org/10.3311/PPch.21222

Abstract

The number of the cyclodextrin-containing drug formulations on the market has been continuously growing since the first drug (prostaglandin E1 formulated with α-cyclodextrin) was launched in Japan in 1976. We have collected a list of drugs from various sources available on the internet to find 130 approved pharmaceutical ingredients formulated with either parent cyclodextrins or their hydroxypropyl, sulfobutyl, random methylated or sulfolipo derivatives. We have sorted the drug products according to the cavity size of the cyclodextrins, the administration route and dosage forms.

Keywords:

approved pharmaceutical products, cyclodextrins, hydroxypropyl cyclodextrin, sulfobutyl cyclodextrin, random methylated cyclodextrin

Published Online

2023-02-01

How to Cite

Puskás, I., Szente, L., Szőcs, L., Fenyvesi, Éva “Recent List of Cyclodextrin-Containing Drug Products”, Periodica Polytechnica Chemical Engineering, 67(1), pp. 11–17, 2023. https://doi.org/10.3311/PPch.21222

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Section

Articles