Immobilization of lipases from Rhizomucor miehei and Thermomyces lanuginosus by adsorption on variously grafted silica gels

Authors

  • László Nagy-Győr
    Affiliation
    Department of Organic Chemistry and Technology, Budapest University of Technology and Economics
  • Zoltán Boros
    Affiliation
    Department of Organic Chemistry and Technology, Budapest University of Technology and Economics
  • László Poppe
    Affiliation
    Department of Organic Chemistry and Technology, Budapest University of Technology and Economics
https://doi.org/10.3311/PPch.2168

Abstract

Twenty variously surface-modified mesoporous silica gels were studied as carriers for immobilization by hydrophobic adsorption of the lipases from Rhizomucor miehei (RmL) and Thermomyces lanuginosus (TlL). Several of the surfacemodified silica gels studied proved to be advantageous supports for RmL and TlL resulting in novel biocatalysts of high activity and enantioselectivity in the kinetic resolution of racemic 1-phenylethanol rac-1. The fact that it were different grafting methods which led to the most efficient supports for RmL and TlL indicated that the selection of optimal support for the immobilization of a particular lipase cannot be predicted.

Keywords:

silica gel, surface modification, kinetic resolution, lipase, immobilization, Rhizomucor miehei, Thermomyces lanuginosus

Citation data from Crossref and Scopus

Published Online

2013-06-26

How to Cite

Nagy-Győr, L., Boros, Z., Poppe, L. “Immobilization of lipases from Rhizomucor miehei and Thermomyces lanuginosus by adsorption on variously grafted silica gels”, Periodica Polytechnica Chemical Engineering, 57(1-2), pp. 37–40, 2013. https://doi.org/10.3311/PPch.2168

Issue

Section

Articles