Optimization of Ultrasound-Assisted Extraction of Total Extractive Substances from Galium verum L.

  • Katarina Rajković
  • Sanja Jeremić
  • Petar S. Milić
  • Marina Kostić
  • Valentina Arsić-Arsenijević
  • Marijana Gavrilović
  • Boro Krstić

Abstract

Ultrasound-assisted extraction (US-AE) of total extractive substances from the herb Lady`s Bedstraw (Galium verum L.) is useful extraction method for its application in food manufacturing. The effect of different temperatures (T) and solvent-to-solid ratios (S) on the US-AE extraction yield was studied in this paper. The influence and optimum of the operating parameters (T and S) was investigated using response surface methodology (RSM). The T and S had impact on extraction yield. RSM showed that the optimal extraction parameters, which gave a maximum extraction yield of 18.7%, were T of 40 oC and S of 30 kg kg-1. Using modeled optimized conditions, detected relative difference between predicted and experimental yield was 3.3 %. RSM successfully predicted optimal parameters and proved as useful tool for standardization of extraction conditions for bioactive components from plants important for food industry.

Keywords: Galium verum L., Optimization, Response surface methodology, Ultrasound-assisted extraction
Published online
2016-10-13
How to Cite
Rajković, K., Jeremić, S., Milić, P., Kostić, M., Arsić-Arsenijević, V., Gavrilović, M. and Krstić, B. (2017) “Optimization of Ultrasound-Assisted Extraction of Total Extractive Substances from Galium verum L.”, Periodica Polytechnica Chemical Engineering, 61(3), pp. 200-205. doi: https://doi.org/10.3311/PPch.9580.
Section
Articles